The Nahe wine region is set west of Rheinhessen, which it borders, and east of the Mosel. Bad Kreuznach is the region's most important town. The Nahe's vineyards thrive in a variety of soils along the steep slopes of the Nahe River and its tributaries.

The more northerly district of Nahe wine region with its loam and sandy soil produces wines that resernble neighbouring Rheinhessen, while the slaty soil further south yields wines which suggest the fine flowery bouquet of Mosel wines and the elegance of Rheingau wines.

Müller-Thurgau, Riesling and Silvaner are the predominant varieties planted in the Nahe wine region.